1. Download reshade 3.0.6 from https://reshade.me/ 

2. Place the Reshade Setup in the the main game folder and run it (May have to run as admin)

3. Select Fallout 4 (Not the launcher/F4SE)

4. Select the Direct3D10+

5. Allow it to download everything

6. Paste Betterlookingv2 and reshade-shaders into the main game folder and overwrite when prompted

7. In-Game press shift+f2, click continue

8. At the top click the drop down and click Betterlookingv2

9. Now the shaders should be set and you can press shift+f2 and play


Enjoy!