Credits:
First, credit to mortealre for "Different power of potions weapons armors runes" - where I got the images and code for the 6 additional runes. Also, credit to Kindo for "CEO" - the modified runes from his mod were the basis of some of my runes, although all were still altered in some way.

Description:
By act 3, I decided I was never really excited about adding runes, the decision of which rune to add was never very difficult, and the selection of runes was leaving a lot to be desired. I already had Kindo's CEO installed, so I searched Nexus Mods for any rune replacements and came across mortealre's Different power of potions weapons armors runes mod. This mod was a complete rebalance of all items in the game, but since I was already in Act 3 and I was happy with everything else from CEO, I decided to unzip his dzip and just modify my CookedPC. Still, I didn't really like the balance of mortealre's runes, so I started modifying his and Kindo's to find a decent balance between power, utility, and selection. In the end, I ended up with 11 different runes that I will often stare at for quite a while in game before deciding which to go with.

Runes:

Rune of Sun: 
Damage 2-1
Bleed +10%
Vitality Combat Regeneration + .5

Rune of Earth:
Damage Reduction on Block +4
Vitality +30
Poison +10%

Rune of Moon:
Sign Damage +5
Freeze +10%
Vigor Combat Regeneration +5%

Rune of Fire:
Adrenaline on Hit +1
Incinerate +10%
Chance of instant kill +2%

Rune of Ysgith:
Damage 3-2
Vitality Combat Regeneration +.5
Vigor Combat Regeneration +5%

Rune of Air:
Knockdown +5%
Stun +5%
Sign Damage +8
Vigor +1

Rune of Sky:
Vitality Combat Regeneration +.5
Endurance Combat Regeneration +.5
Vitality +50
Damage Reduction on Block +6

Rune of Night:
Backstab Bonus +25%
Freeze +10%
Damage +7%

Rune of Water:
Freeze +8%
Incinerate +8%
Poison +8%
Bleed +8%

Rune of Day:
Adrenaline on hit +1
Incinerate +10%
Vitality Combat Regeneration +.5
Vigor Combat Regeneration +5%

Rune of Blisk:
Sign Damage +10
Vigor Combat Regeneration + 5%
Vigor +1
Sign Intensity +5%

Shops:
I've added a 100% chance for all runes and schematics to be at the Mysterious Merchants in Acts 1 and 2 as well as Bras in Act 3.

Installation:
If you have no mods that change runes, schematics, shops, or rune stats - copy the CookedPC folder into your Witcher 2 directory and choose to merge folders and replace all files. 

If you want to merge this with other mods - open each .xml file with a text editor (notepad) and copy and paste what you want to add to the relevant file in your CookedPC folder. Careful, incorrect manipulation will lead to instability. If you get a "Changelist" error when launching the game, you've made a syntax error somewhere.

Files:
Improved Runes>CookedPC>globals>gui>icons>items
runeofair _64x64.dds
runeofblisk _64x64.dds
runeofday _64x64.dds
runeofnight _64x64.dds
runeofsky _64x64.dds
runeofwater _64x64.dds
zzz0 _64x64.dds
zzz1 _64x64.dds
zzz2 _64x64.dds
zzz3 _64x64.dds
zzz4 _64x64.dds
zzz5 _64x64.dds
zzz6 _64x64.dds

Improved Runes>CookedPC>items
def_item_runes.xml
def_item_schematics.xml
def_shops.xml
def_stats_item_runes.xml

The CookedPC>globals>gui>icons>items folder contains the icons for the runes and schematics. I couldn't get the schematic icons to work without using mortealre's en0.w2strings file, which I didn't want to deal with. You'll live. Feel free to try yourself.

Compatibility:
Tested with Enhanced Edition version 3.4 and with A TON of mods installed (as well as vanilla). The files I've included are based on the vanilla game to make additional modifications the easiest. I can make it compatible with any mod if you let me know.

Distribution:
Do whatever you want with it. I couldn't care less. Just give me a shout out.

Any questions or problems let me know.